The Foundational Hormones Behind Energy, Metabolism, and Recovery
Thyroid hormone, DHEA, and melatonin sit underneath almost everything patients come to us about, energy, body composition, mood, sleep, and recovery all trace back to whether these signals are working the way they should. Testosterone, estradiol, and progesterone are covered in depth in Men's Health and Women's Health, since the evidence and dosing questions around them are sex-specific enough to deserve their own space.
Which Hormone Are You Actually Asking About?
This page covers thyroid hormone, DHEA, and melatonin specifically. If you came here about testosterone, estradiol, or progesterone, or you are not yet sure hormone therapy is right for you at all, start in the right place below.
Not Sure If Therapy Is Right for You?
Before any guide on this site, start with a plain answer to whether hormone or peptide optimization actually fits your situation.
Is This Right for Me? 02Looking for Testosterone, Estradiol, or Progesterone?
Those are covered further down this page, organized by the population most patients ask about them for.
Jump to Sex Hormones 03Want Every Guide, Not Just Thyroid, DHEA, and Melatonin?
See the complete evidence-graded library: mechanism, trial data, dosing considerations, and honest research gaps, for every hormone and peptide on this site.
Explore the Knowledge CenterSignals First, Symptoms Second
Every guide below is written through the same lens: what receptor or pathway a hormone acts on, what that changes at the cellular and metabolic level, and only then what a patient actually feels or measures. If you want the full framework behind that approach, it's laid out on the Cellular Medicine page.
Thyroid, DHEA, and Melatonin
Desiccated Thyroid
What natural desiccated thyroid is, how it differs from synthetic T4-only therapy, and where the evidence actually supports its use.
Read the Guide AdrenalDHEA
The adrenal precursor hormone that feeds into both androgen and estrogen pathways, and what the human trial data does and doesn't show.
Read the Guide PinealMelatonin
The circadian-timing hormone behind most sleep aid supplements, what the trial evidence actually supports, and why supplement quality is a bigger issue here than for prescription hormones.
Read the GuideTestosterone, Estradiol, and Progesterone
These are hormones too, and the same evidence standard applies. They're organized by the population most of our patients ask about them for.
Common Questions
Have a Question, or Want to Find a Clinic?
If you're already a patient, bring this up with your care team at your next visit. If you're not a patient yet and want to ask a question first, or find one of our clinics, reach out directly.