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Physician-written perspectives on the latest research and the questions patients ask most. Start with the newest article below, or explore a topic.

Darrell Wilcox, MD 10/12/26 Darrell Wilcox, MD 10/12/26

Your Coffee Isn't Fixing Your Fatigue. It's Hiding It.

If more coffee keeps being the answer and the tiredness never actually lifts, that's not a caffeine tolerance problem. It's two different physiological states being treated as one.

Darrell Wilcox, MD 9/25/26 Darrell Wilcox, MD 9/25/26

Does Progesterone Cause Bloating? What the Research Actually Shows

Progesterone gets blamed for bloating and breast tenderness on hormone therapy, but it actually blocks the receptor that causes fluid retention. Here's what's really going on.

Darrell Wilcox, MD 9/11/26 Darrell Wilcox, MD 9/11/26

Does Progesterone Cause Brain Tumors? What the Research Actually Shows

A meningioma headline about progesterone is usually actually about one specific synthetic progestin. Here's what the research shows about which ones carry real risk, and which don't.

Darrell Wilcox, MD 8/28/26 Darrell Wilcox, MD 8/28/26

Adrenal Fatigue Isn't a Diagnosis. Cellular Cortisol Resistance Is.

Adrenal fatigue is not a standard medical diagnosis. Symptoms can be real even when that label is wrong. Chronic stress can mute how cells hear cortisol while blood levels still look fine.

Darrell Wilcox, MD 4/18/26 Darrell Wilcox, MD 4/18/26

Why Your Labs Look Normal But You Feel Terrible

Your doctor says your labs are fine. So why do you still feel exhausted, foggy, and off? The problem isn't your results — it's what "normal" actually means, and what most standard panels never measure.